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Carnitine Shuttle and Ferroptosis in Cancer

10.3390/nano11051270 42 DingY.DingL.XiaY.WangF.ZhuC

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2.8.2 Clinical studies Increased accumulation of iron in substantia nigra of PD patients was observed with MRI techniques in post mortem studies with significant accumulation in putamen, red nucleus, nucleus caudatus and globus pallidus (Wang et al., 2016) and similar imaging findings on nigrosome imaging were found in cases of PD and parkinsonian syndromes (Li et al., 2022)